Type Of Breast Reconstruction Impacts Radiation Therapy OutcomesFor breast cancer patients who underwent a mastectomy who undergo radiation therapy after immediate breast reconstruction, autologous tissue reconstruction provides fewer long-term complications and better cosmetic results than tissue expander and implant reconstruction, according to a study in the November issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Therapeutic Radiology and Oncology.
Randomized Phase 2 Study Of IMC-A12 For HER2-Expressing Advanced Breast Cancer Commences Patient EnrollmentImClone Systems Incorporated (NASDAQ: IMCL), a global leader in the development and commercialization of novel antibodies to treat cancer, today announced that its disease-directed randomized Phase 2 clinical trial of IMC-A12 in patients with previously treated HER2-expressing locally advanced or metastatic breast cancer has commenced patient enrollment. IMC-A12 is ImClone's fully human, IgG1 anti-insulin-like growth factor-1 receptor (IGF-1R) monoclonal antibody.
Causes Of Bone Loss In Breast Cancer Survivors Identified By StudyOsteoporosis is a growing concern among breast cancer survivors and their doctors, because certain cancer drugs can cause bone loss. But a new study has found that cancer drugs aren't the only culprits. Among 64 breast cancer patients referred to a bone health clinic, 78 percent had at least one other cause of bone loss, including vitamin D deficiency, excessive calcium excretion in urine and an overactive parathyroid gland.
Two New Compounds Show Promise For Destroying Breast Cancer Tumors - University Of Central FloridaTwo new compounds created by a University of Central Florida professor show early promise for destroying breast cancer tumors. Associate Professor James Turkson's compounds disrupt the formation and spread of breast cancer tumors in tests on mice. The compounds, S3I-201 and S3I-M2001, break up a cancer-causing protein called STAT3, and researchers have observed no negative side effects so far. "The compounds are very promising," Turkson said.
Breast Cancer Prevention Differences In Postmenopausal Women Following Calorie Restriction And ExerciseScientists at the University of Texas at Austin have identified pathways by which a reduced-calorie diet and exercise can modify a postmenopausal woman's risk of breast cancer. The results, presented at the American Association for Cancer Research's Seventh Annual International Conference on Frontiers in Cancer Prevention Research, suggest that both caloric restriction and exercise affect pathways leading to mTOR, a molecule involved in integrating energy balance with cell growth.
Survival In Breast Cancer Patients Boosted By Intervention ProgramA new study provides the best evidence to date that a psychological intervention program designed for breast cancer patients not only improves their health - it actually increases their chance of survival. Researchers at Ohio State University's Comprehensive Cancer Center found that patients participating in an intervention program reduced their risk of dying of breast cancer by 56 percent after an average of 11 years.
Community Factors Predict Reconstruction After Mastectomy According to new research published in the November issue of Archives of Surgery, women who live in wealthier communities with lower population densities and a larger proportion of college-educated individuals are more likely to have immediate breast reconstruction after mastectomy. Every year in the Unites States, breast cancer affects 134 of every 100,000 women.
Teaching Breast Health Early To Reduce Breast Cancer Mortality In D.C.Early breast health education may be the key to lowering breast cancer mortality rates in Washington, D.C., which has the highest rates in the country, according to research presented at the American Association for Cancer Research's Seventh Annual International Conference on Frontiers in Cancer Prevention Research.
ER/PR Negative Tumors Associated With Insurance StatusAfrican-American women are at a higher risk for ER/PR negative breast cancer. A new study, to be presented at the American Association for Cancer Research's Seventh Annual International Conference on Frontiers in Cancer Prevention Research, found that race, socioeconomic characteristics and other tumor characteristics are all important predictors of having ER/PR negative breast cancer.
Studies To Examine Factors Behind Racial Disparities In Breast, Colon CancersThe following summarizes articles about two cancer studies that examine racial disparities. Breast cancer: Researchers from the University of North Carolina's Lineberger Comprehensive Cancer Center are expanding the Carolina Breast Cancer Study to examine why black women are more likely than white women to die from the disease, the
Dangerous 'Two-Faced' Protein Crucial To Breast Cancer Spread And Growth Identified By Mayo ResearchersTwo critical properties of cancer cells are their ability to divide without restraint and to spread away from the primary tumor to establish new tumor sites. Now, researchers from the Mayo Clinic campus in Florida have found a protein they say acts as a deadly master switch, both freeing cancer cells from a tumor while ramping up new growth. This is potentially good news, say the researchers, who published their study in the Nov. 17 issue of the Journal of Cell Biology.